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circulating functional biomarkers

Genomic biomarkers

Genomic biomarkers, such as PNPLA3 and TM6SF2, are increasingly used to enrich clinical study populations for genotypes associated with certain disease phenotypes.

circulating functional biomarkers

Fibrosome biomarkers

Biomarkers are used to capture tissue-specific markers of fibrogenesis and fibrolysis. Some examples are the ELF panel, FIB-4, and various collagen precursors, such as PRO-C3.

circulating functional biomarkers

Inflammasome biomarkers

Biomarkers, such as TGF-β1, CRP and others, are used to assess inflammatory activity levels, which may indicate disease activity or risk of progression.

circulating functional biomarkers

Metabolome biomarkers

Biomarkers are used to assess pathway-specific metabolites, such as those that represent disease activity. For example, lipidomic markers can indicate stages of NAFLD or NASH.

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