GLY-200, an oral pharmacologic duodenal exclusion drug, resulted in positive effects on glucose, lipids and bodyweight in patients with type 2 diabetes: Results of a randomized, double-blind placebo-controlled trial

Article Authors: Christine L. N. Bryant PhD, Kevin Colbert MS, Marcus Hompesch MD, SuZanne Chaves MD, Ashish Nimgaonkar MD, Mark S. Fineman PhD

Publication Date: 08/06/2025

Publication: Diabetes, Obesity and Metabolism

About This Article

An article published in Diabetes, Obesity and Metabolism, co-authored by Glyscend Therapeutics and ProSciento, discusses findings from a study that examined the effects of GLY-200, an oral pharmacologic duodenal exclusion drug, in patients with type 2 diabetes and obesity. The study demonstrated significant improvements in glucose control, lipid profiles, and body weight, highlighting GLY-200’s potential as a non-invasive therapeutic option for managing metabolic diseases.

GLY-200, an oral pharmacologic duodenal exclusion drug, resulted in positive effects on glucose, lipids and bodyweight in patients with type 2 diabetes: Results of a randomized, double-blind placebo-controlled trial thumbnail