Turning Metabolic Complexity into Clinical Clarity

Advise. Advance. Achieve.

The Metabolic Continuum Is Complex. Your Partner Shouldn't Be.

ProSciento is a specialized contract research organization (CRO) built around one scientific domain: the metabolic continuum. From diabetes and obesity to MASLD/MASH, cardiovascular disease, chronic kidney disease, and beyond — we bring clinical expertise, proven infrastructure, and genuine scientific depth to every program we support. This is our mission. 

Why Partner with ProSciento?

Over two decades of delivering what matters in research.
We’re With You For Every Step – From Strategy Through Study Completion 
Clinical development takes unexpected turns and we move with you through every one. From early scientific strategy through Phase 3, we engage as a fully integrated partner, not a vendor for handoffs. Our scientific fluency and operational discipline mean you get the same expertise, focus, and commitment at every stage of the journey, from the first conversation to the final deliverable. 
We See the Full Picture: Not An Isolated Disease
Metabolic diseases are interconnected, and we treat them that way. A patient with obesity carries cardiovascular risk. A diabetes program touches the liver. These connections are central to doing this work well, and that understanding shapes every protocol we design, every study we run, and every recommendation we make. 
Access That Takes Years to Build  
Our nationwide registry of 180,000+ participants, each with 200+ metabolic characterization data points, didn’t come from a technology investment. It came from two decades of genuine relationships with participants and sites. The result: more accurate feasibility, stronger recruitment, and better retention. 

See the Connection. Advance the Science.

These conditions share common risk factors, overlapping biology, and compounding effects on patients. Understanding how they connect leads to stronger science and, ultimately, better treatments for the people living with them.

See the Connection. Advance the Science.

These conditions share common risk factors, overlapping biology, and compounding effects on patients. Understanding how they connect leads to stronger science and, ultimately, better treatments for the people living with them.

Every Stage. Every Capability.
One Team. 

ProSciento is a full-service CRO built to support every stage of clinical development. Each capability we offer is intentionally designed to leverage our expertise and drive consistent operational excellence, from first-in-human studies through Phase 3 and beyond.

Contract Research Organization (CRO)

Global clinical trial execution with metabolic expertise at its core.
Full-service clinical trial execution from startup through completion, delivered globally with deep metabolic expertise embedded at every level. Our teams support regulatory affairs, medical writing, feasibility, site selection, clinical and project management, data management, and pharmacovigilance across a network of 250+ clinical sites, all through a single, integrated point of contact.

Clinical and Regulatory Development (CRD)

Scientific and regulatory strategy for the earliest stages of clinical development.

We engage with clients at the earliest stages of development, helping clarify the science, strategy, and regulatory pathway before a program is formally underway. Early decisions shaped by the right expertise strengthen everything that follows.

  • Regulatory affairs support
  • Medical writing
  • Feasibility
  • Site selection
  • Clinical and project management
  • Data management
  • Pharmacovigilance
  • Medical monitoring

Clinical Research Unit (CRU)

State-of-the-art in-house research dedicated to early metabolic studies.
Our clinical research unit is built for the complexity and rigor of early metabolic disease research — work that demands deep scientific specialization and precise execution. With a 30,000 sq ft facility, 30+ beds, 15+ glucose clamp beds, a CLIA-certified laboratory, and 24/7 on-site medical and clinical teams, clients have access to in-house capabilities that bring academic-level sophistication to a dedicated private research setting. From first-in-human through early-phase studies, this means direct participant access, faster startup, and a team with deep expertise in this science.

Participant and Site Support (PSS)

A relationship-centered approach to participant and site engagement
A proprietary database of 180,000+ participants with 200+ metabolic characterization data points gives us exceptional visibility into participant populations across the metabolic continuum. Combined with direct, ongoing relationships with participants and sites, this enables more informed feasibility assessments, more reliable enrollment planning, and stronger retention throughout the study. Built on genuine engagement, these relationships extend well beyond any single study.

Clinical Research Innovation (CRI)

Advancing metabolic disease science through research, publication, and scientific leadership.
ProSciento actively contributes to metabolic disease science in clinical practice and across the broader academic community. Through peer-reviewed publications, translational research, editorial leadership of an international scientific journal, and of a widely recognized textbook in the field, ProSciento helps shape how metabolic diseases are studied and understood. These insights flow directly into study design and execution, ensuring clients benefit from current, scientifically grounded approaches.

Proven experience. Measurable results.

250+

Clinical trial sites globally

55

Method hubs

180,000+

Participants in our proprietary database

175+

FDA submissions

20

Approved therapeutics supported through clinical development

100+

Early clinical development protocols developed

30,000 sq ft

State-of-the-art clinical research unit

What’s New at ProSciento

Our latest updates and announcements

Your development journey
starts with a conversation.