Short-term metabolic effects of prednisone administration in healthy subjects

Article Authors: E A Kauh, L A Mixson, S Shankar, J McCarthy, V Maridakis, L Morrow, L Heinemann, M K Ruddy, G A Herman, D E Kelley, M Hompesch


Supraphysiologic glucocorticoid activity is well established to cause impaired glucose tolerance and insulin resistance, yet no study has evaluated dose-dependent effects of low-dose prednisone during short-term oral administration.