Glucose, Lipid And Mixed-meal Tolerance Tests

Oral glucose, oral lipid, and mixed-meal tolerance tests are specialized methods ProSciento uses in metabolic research to assess glucose response to a therapeutic intervention, as well as provide exploratory data on insulin secretion and insulin sensitivity. They provide an integrated assessment of the metabolic responses relevant when assessing an intervention. ProSciento’s expertise in metabolic diseases enables the design and management of diet input and response studies.

Glucose, Lipid And Mixed-meal Tolerance Tests

Tolerance Testing Techniques For Metabolic Trials

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Oral Glucose Tolerance Test

Oral glucose tolerance test (OGTT) is used to interrogate the effects of a therapeutic intervention in a clinical research setting and by clinicians to diagnose forms of glucose intolerance and type 2 diabetes.

Mixed-Meal Tolerance Test

Mixed Meal Tolerance Test (MMTT) provides a more comprehensive physiological stimulus to insulin secretion since 13-cells are responsive to certain amino acids and fatty acids in addition to glucose.

Oral Lipid Tolerance Test

Oral lipid tolerance test (OLTT) is used to measure postprandial triglyceride levels and whole-body lipid homeostasis after consumption of a standardized meal.

To learn more about tolerance testing techniques and clinical R&D services for single and multi-site studies, contact bd@prosciento.com.