What is Indirect Calorimetry

Indirect calorimetry is a non-invasive technique that yields sensitive and accurate data on energy expenditure and substrate utilization, which is fundamental for the understanding of metabolism. ProSciento utilizes indirect calorimetry as a specialized method in clinical trials to access nutrient assimilation, thermogenesis, the effect of physical activity, and the pathologic mechanisms of obesity and diabetes.

Indirect calorimetry is further used to study the interrelation between energy expenditure, diet manipulation, and the genetic influence in obese individuals, as well as accessing alterations in insulin resistance in patient and healthy populations.

What is Indirect Calorimetry

Indirect Calorimetry Metabolic Endpoints

Basal energy expenditure (EE) or resting EE (REE) is the energy to sustain the basic life functions at rest.

Diet-induced thermogenesis is the energy used during metabolism postprandial.

Activity energy expenditure (AEE) is the energy consumed by physical activity.

Substrate oxidation and respiratory quotient (RQ) is the ratio of carbon dioxide produced for amount of oxygen consumed.

To learn more about indirect calorimetry techniques for metabolic clinical research, contact bd@prosciento.com.